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US Patent 9556188 Substituted imidazo[1,2-b]pyrazoles as bruton'S tyrosine kinase modulators

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Date of Patent

January 31, 2017

Patent Application Number

14951494

Date Filed

November 25, 2015

Patent Citations Received

US Patent 12103931 Crystalline form of (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo[1,5-a]pyrimidine-3-carboxamide, preparation, and uses thereof

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US Patent 11911386 Methods of treating B-cell proliferative disorder

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US Patent 11970500 Crystalline form of (s)-7-(1-acryloylpiperidin-4-yl)- 2-(4-phenoxyphenyl)-4,5,6,7-tetra- hydropyrazolo[1,5-a]pyrimidine-3-carboxamide, preparation, and uses thereof

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US Patent 11999743 Crystalline form of (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo[1,5-a]pyrimidine-3-carboxamide, preparation, and uses thereof

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US Patent 11701357 Treatment of B cell cancers using a combination comprising Btk inhibitors

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US Patent 11786531 Methods of treating B-cell proliferative disorder

US Patent 11786529 Treatment of indolent or aggressive B-cell lymphomas using a combination comprising BTK inhibitors

US Patent 11851437 Crystalline form of (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo[1,5-a]pyrimidine-3-carboxamide, preparation, and uses thereof

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Patent Primary Examiner

Douglas M Willis

Patent abstract

The invention is fused heterocyclic compounds of formula (I), and salts thereof, compositions thereof, and methods of use therefor. In particular, disclosed herein are certain fused heterocyclic compounds that can be useful for inhibiting protein kinase, including Bruton's tyrosine kinase (Btk), and for treating disorders mediated thereby.

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